Symposia
Understanding of Alzheimer’s disease and development of the disease model for drug discovery／アルツハイマー病のクスリ創りー病気の理解と病態モデルー |
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| 3S9
Development of drugs for Alzheimer’s disease is one of urgent issues in the aging society. To develop drugs for central nervous system disorders such as Alzheimer’s disease, it is required to evaluate drug effects on synaptic function which governs learning and memory. In addition, development of a good model to predict side effects of developing drugs in the early state of drug discovery is demanded. Although a few good models have been developed, usage of human induced pluripotent stem cells has also a high potential for becoming a good model. In this symposium, Drs. Mikio Shoji and Takaomi C. Saido will discuss current situation of Alzheimer’s disease and its drugs in clinical practice, and development of model mice or neurons of Alzheimer’s disease. Furthermore, Dr. Tomoaki Shirao will introduce our recent project entitled “An in vitro pharmacological assessment of brain function for drug discovery and the development of the standardized human neurons”.
Development of drugs for Alzheimer’s disease is one of urgent issues in the aging society. To develop drugs for central nervous system disorders such as Alzheimer’s disease, it is required to evaluate drug effects on synaptic function which governs learning and memory. In addition, development of a good model to predict side effects of developing drugs in the early state of drug discovery is demanded. Although a few good models have been developed, usage of human induced pluripotent stem cells has also a high potential for becoming a good model. In this symposium, Drs. Mikio Shoji and Takaomi C. Saido will discuss current situation of Alzheimer’s disease and its drugs in clinical practice, and development of model mice or neurons of Alzheimer’s disease. Furthermore, Dr. Tomoaki Shirao will introduce our recent project entitled “An in vitro pharmacological assessment of brain function for drug discovery and the development of the standardized human neurons”. | | | |
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