| 会長招聘講演 |
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| 1L3
Oxytocin and more：what we have learned from the brain development and its disorders
Sato Makoto1,2,3
1Department of Anatomy and Neuroscience, Osaka University Graduate School of Medicine，2United Graduate School of Child Development, Osaka University，3Research Center for Child Mental Development, University of Fukui
Autism spectrum disorders（ASD）is not a sole disorder but a group of disorders, which is characterized by persistent deficits in social communication and social interaction as well as restricted, repetitive patterns of behavior and/or interests. So far, there exist no verified treatments for ASD. Oxytocin has attracts much attention for its potential as a new pharmacological treatment for ASD. Several studies demonstrated that an application of a single-dose of oxytocin nasal spray results in an improvement of the social communication of ASD patient for a while, but whether a continuous oxytocin application has pro-longed therapeutic effects or not remains open. Our Research Center for Child Mental Development at University of Fukui found that such continuous application is effective for a limited group of patients. This observation reinforced the concept that ASD is a mixture of disorders of which etiologies are varied. To elucidate such etiologies, we examined the role of specific neurons, of which function is likely to be involved in ASD characteristics as well as neural networks. In my talk, I will also introduce our recent attempts of such studies. | | | |
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